The connection between art and medicine can be a hard link to find at first. Whereas the founder of medicine Hippocrates, can be traced back to 460 BC3, art has been around since the beginning of time as a form of documentation. Art and medicine can be compiled together, to engage with patients, making them understand more about the world of medicine. Physicians have increased their understanding of the human body by anatomical drawings done by great artists such as Leonardo Da Vinci and William Hunter. Furthermore medicine in art has gone from portraying sin in the 18th century to mental illness in the 20th century, displaying how medicine is canvassed all around us. Such famous works such as ‘The Scream’ by Edvard Munch and ‘Icarus’ by Matisse are discussed in this review, showing the artist’s influence on portrayal of the medical world. Art is also used as a tool in art therapy and to add colour to bland hospital walls. Art is definitely becoming more prominent in everyday practice. Vast links can be made between art and medicine, looking at how each world influences another. Some are described in this special study module.